The list of the vascular plants specimens of Tohma valley (Malatya-Sivas) was given in this study. 1816 plant specimens were collected from the research area between 2007-2015 years. At the end of the identification of the collected specimens and the results of previous studies, 81 families, 353 genera, 847 species, 18 sub-species, 6 varieties and 871 taxa in total were determined. The largest 3 families are Asteraceae (102 species), Brassicaceae (78 species) and Fabaceae (77 species). The largest 4 genera are Astragalus (31 species), Alys- sum (17 species), Onosma (14 species) and Salvia (14 species). The phytogeographical spectrum of the species is as follows: Irano-Turanian elements 298 (35.18%), Mediterranean elements 39 (4.60%) and Euro-Siberian elements 27 (3.18%) and multi-regional or phytogeographical unknown 483 (57.02%). The number of endemic species in the research area was determined as 169 (20%). At the same time, new IUCN categories of twelve taxa were proposed.