In this study, was investigated in vitro antimicrobial and antioxidant activities and GC/MS analysis of the essential oil of Rumex crispus and Rumex cristatus collected from Corum province and around. Total antio- xidant status of essential oils prepared with ethanol and pure water were measured spectrophotometrically. Staphylococcus aureus ATCC 25923, Eschrechia coli ATCC 25922, Enterecoccus faecalis ATCC 29212 and Can- dida albicans ATCC 10231 were used to the antimicrobial studies. The antimicrobial properties of samples were determinate with the disk diffusion and agar-well method. The total antioxidant status in the essential oils of all Rumex cristatus contained high levels was determinate according to Rumex crispus. The developing of test microorganisms of the essential oils of all Rumex crispus and Rumex cristatus extracts have been observed to inhibit varying degrees on the antimicrobial activity test. Furthermore, extracts obtained with ethanol is more effective according to chloroform extracts and more efficient results which have been identified. Enterecoc- cus faecalis ATCC 29212, Escherichia coli ATCC 25922 Staphylococcus aureus ATCC 25923 and fungal culture of Candida albicans ATCC 10231. The diphenic acid derivatives were found the content of two Rumex sp. essential oils with GC/MS analysis.